ID   HMCU_DROME     STANDARD;      PRT;  2175 AA.
AC   P10180;
DT   01-MAR-1989 (REL. 10, CREATED)
DT   01-MAR-1989 (REL. 10, LAST SEQUENCE UPDATE)
DT   01-MAY-1992 (REL. 22, LAST ANNOTATION UPDATE)
DE   HOMEOBOX PROTEIN CUT.
GN   CT.
OS   DROSOPHILA MELANOGASTER (FRUIT FLY).
OC   EUKARYOTA; METAZOA; ARTHROPODA; INSECTA; DIPTERA.
RN   [1]
RP   SEQUENCE FROM N.A.
RM   88232956
RA   BLOCHLINGER K., BODMER R., JACK J., JAN L.Y., JAN Y.N.;
RL   NATURE 333:629-635(1988).
CC   -!- FUNCTION: CUT IS INVOLVED IN SPECIFYING SENSORY ORGAN IDENTITY IN
CC       FRUIT FLY. IN ABSENCE OF CUT GENE EXTERNAL SENSORY ORGANS ARE
CC       TRANSFORMED INTO CHORDOTONAL ORGANS.
DR   EMBL; X07985; DMCUT.
DR   PIR; S03170; S03170.
DR   TFD; P00024; RELEASE 3.0.
DR   TFD; P00025; RELEASE 3.0.
DR   TFD; P00026; RELEASE 3.0.
DR   FLYBASE; 04198; RELEASE 9206.
DR   PROSITE; PS00027; HOMEOBOX.
KW   HOMEOBOX; DNA-BINDING; DEVELOPMENTAL PROTEIN; NUCLEAR PROTEIN;
KW   REPEAT.
FT   DOMAIN      194    210       ALA/GLN-RICH.
FT   DOMAIN      235    243       ALA-RICH.
FT   DOMAIN      271    293       ASP/GLU-RICH (ACIDIC).
FT   DOMAIN      384    428       ASN-RICH.
FT   DOMAIN      547    554       ASP/GLU-RICH (ACIDIC).
FT   DOMAIN      574    584       ASP/GLU-RICH (ACIDIC).
FT   DOMAIN      616    630       ALA-RICH.
FT   DOMAIN      665    699       HIS/GLN-RICH.
FT   REPEAT      886    945       'CUT'-REPEAT.
FT   REPEAT     1339   1398       'CUT'-REPEAT.
FT   REPEAT     1617   1676       'CUT'-REPEAT.
FT   DNA_BIND   1745   1804       HOMEOBOX.
FT   DOMAIN     2004   2014       ALA-RICH.
FT   DOMAIN     2071   2077       ASP/GLU-RICH (ACIDIC).
FT   DOMAIN     2124   2136       ALA/PRO-RICH.
SQ   SEQUENCE   2175 AA;  233628 MW;  1.697006E+07 CN;
       1  MQPTLPQAAG TADMDLTAVQ SINDWFFKKE QIYLLAQFWQ QRATLAEKEV NTLKEQLSTG
      61  NPDSNLNSEN SDTAAAAATA AAVAAVVAGA TATNDIEDEQ QQQLQQTASG GILESDSDKL
     121  LNSSIVAAAI TLQQQNGSNL LANTNTPSPS PPLLSAEQQQ QLQSSLQQSG GVGGACLNPK
     181  LFFNHAQQMM MMEAAAAAAA AALQQQQQQQ SPLHSPANEV AIPTEQPAAT VATGAAAAAA
     241  AAATPIATGN VKSGSTTSNA NHTNSNNSHQ DEEELDDEEE DEEEDEDEDD EEENASMQSN
     301  ADDMELDAQQ ETRTEPSATT QQQHQQQDTE DLEENKDAGE ASLNVSNNHN TTDSNNSCSR
     361  KNNNGGNESE QHVASSAEDD DCANNNTNTS NNNNTSNTAT SNTNNNNNNN SSSGNSEKRK
     421  KKNNNNNNGQ PAVLLAAKDK EIKALLDELQ RLRAQEQTHL VQIQRLEEHL EVKRQHIIRL
     481  EARLDKQQIN EALAEATALS AAASTNNNNN SQSSDNNKKL NTAAERPMDA SSNADLPEST
     541  KAPVPAEDDE EDEDQAMLVD SEEAEDKPED SHHDDDEDED EDREAVNATT TDSNELKIKK
     601  EQHSPLDLNV LSPNSAIAAA AAAAAAAACA NDPNKFQALL IERTKALAAE ALKNGASDAL
     661  SEDAHHQQQQ HHQQQHQHQQ QHHQQQHLHQ QHHHHLQQQP NSGSNSNPAS NDHHHGHHLH
     721  GHGLLHPSSA HHLHHQTTES NSNSSTPTAA GNNNGSNNSS SNTNANSTAQ LAASLASTLN
     781  GTKSLMQEDS NGLAAVAMAA HAQHAAALGP GFLPGLPAFQ FAAAQVAAGG DGRGHYRFAD
     841  SELQLPPGAS MAGRLGESLI PKGDPMEAKL QEMLRYNMDK YANQALDTLH ISRRVRELLS
     901  VHNIGQRLFA KYILGLSQGT VSELLSKPKP WDKLTEKGRD SYRKMHAWAC DDNAVMLLKS
     961  LIPKKDSGLP QYAGRGAGGA GGDDSMSEDR IAHILSEASS LMKQSSVAQH REQERRSHGG
    1021  EDSHSNEDSK SPPQSCTSPF FKVENQLKQH QHLNPEQAAA QQREREREQR EREQQQRLRH
    1081  DDQDKMARLY QELIARTPRE TAFPSFLFSP SLFGGAAGMP GAASNAFPAM ADENMRHVFE
    1141  REIAKLQQHQ QQQQAAQAQA QFPNFSSLMA LQQQVLNGAQ DLSLAAAAAK DIKLNGQRSS
    1201  LEHSAGSSSC SKDGERDDAY PSSLHGRKSE GGGTPAPPAP PSGPGTGAGA PPTAAPPTGG
    1261  ASSNSAAPSP LSNSILPPAL SSQGEEFAAT ASPLQRMASI TNSLITQPPV TPHHSTPQRP
    1321  TKAVLPPITQ QQFDMFNNLN TEDIVRRVKE ALSQYSISQR LFGESVLGLS QGSVSDLLAR
    1381  PKPWHMLTQK GREPFIRMKM FLEDENAVHK LVASQYKIAP EKLMRTGSYS GSPQMPQGLA
    1441  SKMQAASLPM QKMMSELKLQ EPAQAQHLMQ QMQAAAMSAA MQQQQVAQAQ QQAQQAQQAQ
    1501  QHLQQQAQQH LQQQQHLAQQ QHPHQQHHQA AAAAAALHHQ SMLLTSPGLP PQHAISLPPS
    1561  AGGAQPGGPG GNQGSSNPSN SEKKPMLMPV HGTNAMRSLH QHMSPTVYEM AALTQDLDTH
    1621  DITTKIKEAL LANNIGQKIF GEAVLGLSQG SVSELLSKPK PWHMLSIKGR EPFIRMQLWL
    1681  SDANNVERLQ LLKNERREAS KRRRSTGPNQ QDNSSDTSSN DTNDFYTSSP GPGSVGSGVG
    1741  GAPPSKKQRV LFSEEQKEAL RLAFALDPYP NVGTIEFLAN ELGLATRTIT NWFHNHRMRL
    1801  KQQVPHGPAG QDNPIPSRES TSATPFDPVQ FRILLQQRLL ELHKERMGMS GAPIPYPPYF
    1861  AAAAILGRSL AGIPGAAAAA GAAAAAAAVG ASGGDELQAL NQAFKEQMSG LDLSMPTLKR
    1921  ERSDDYQDDL ELEGGGHNLS DNESLEGQEP EDKTTDYEKV LHKSALAAAA AYMSNAVRSS
    1981  RRKPAAPQWV NPAGAVTNPS AVVAAVAAAA AAAADNERII NGVCVMQASE YGRDDTDSNK
    2041  PTDGGNDSDH EHAQLEIDQR FMEPEVHIKQ EEDDDEEQSG SVNLDNEDNA TSEQKLKVIN
    2101  EEKLRMVRVR RLSSTGGGSS EEMPAPLAPP PPPPAASSSI VSGESTTSSS SSSNTSSSTP
    2161  AVTTAAATAA AGWNY                                                 
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