BMB/BI/CH 170 Syllabus Fall 2017

Biochemistry and Biophysics of Macromolecules and Molecular Assemblies

http://saf.bio.caltech.edu/bi170.html
TUES/THUR 10:30 A.M. - 12 NOON
151 Crellin

Instructors:                                     Teaching Assistants:
Bil Clemons                                       Inha Cho, x4205, icho@caltech.edu, 129 Spalding
 157 Broad, x1796                                 Claudia Jette, x3152, cajette@caltech.edu, 135 Braun
 clemons@caltech.edu                              Jingzhou Wang, x6407, jingzhou@caltech.edu, 150Broad      
 
Suggested Text: Textbook of Structural Biology Liljas, Liljas, Piskur et al

PROTEINS
01  09/26  Introduction, history and basic chemistry                        *1 (CJ)
02  09/28  Peptide bonds and secondary structure

03  10/03  Tertiary structure
04  10/05  Hydrophobic effect and stabilizing forces

05  10/10  Stability, folding, and chaperones                               *2 (IC)
06  10/12  Chaperones continued and aggregates; Motifs, oligomers, assemblies

07  10/17  Cytoskeleton and symmetrical assemblies
08  10/19  Viruses

09  10/24  Metals, enzymes and nucleotide binding proteins                  *3 (IC)
NUCLEIC ACIDS
10  10/26  Basic Chemistry, DNA/RNA structure

11  10/31  Protein interactions, transcription factors

12  11/06  Transcription factors continued and ribosomes
13  11/07  Ribosomes and translation                                        *4 (JW)
MEMBRANES & LIPIDS
14  11/09  Lipids and Biological Membranes

15  11/14  Membrane Protein synthesis and stability
16  11/16  Membrane Proteins continued

CARBOHYDRATES
17  11/21  Basic chemistry and CAZy                                         *5 (JW)
    11/23  Thanksgiving Holiday

18  11/28  More glycozymes and biological roles
19  11/30  Lectins and glycobiology

    12/01  Last problem set due 5PM.

    12/08  Finals due by 5PM. (Bil's office or Claudia)


*n Problem set n handed out.

Last modified 03-NOV-2017