BMB/BI/CH 170 Syllabus Fall 2016

Biochemistry and Biophysics of Macromolecules and Molecular Assemblies

http://saf.bio.caltech.edu/bi170.html
TUES/THUR 10:30 A.M. - 12 NOON
151 Crellin

Instructors:                                     Teaching Assistants:
Bil Clemons                                       Inha Cho, x4205, icho@caltech.edu, 129 Spalding
 157 Broad, x1796                                 Hyun-Gi Yun, x1729, hyun@caltech.edu, B140H Broad
 clemons@caltech.edu                              Stepen Marshall, x1728, smarshal@caltech.edu, B140G Broad
       
 
Suggested Text: Textbook of Structural Biology Liljas, Liljas, Piskur et al

PROTEINS
01  09/27  Introduction, history and basic chemistry                        *1 (HY)
02  09/29  Peptide bonds, energetics, secondary structure

03  10/04  Tertiary structure and the hydrophobic effect
04  10/06  Stability, folding and chaperones

05  10/11  Chaperones and aggregates                                        *2 (IC)
06  10/13  Motifs, oligomer, protein modifications and assemblies

07  10/18  Assemblies continued, virsues and symmetrical assemblies
08  10/20  Metals, enzymes and nucleotide binding proteins

NUCLEIC ACIDS
09  10/25  Basic Chemistry                                                  *3 (IC)
10  10/27  DNA/RNA structure

11  11/01  Protein interactions, transcription factors
12  11/03  Transcription factors, additional interactions and ribosomes

13  11/08  Replication, transcription and translation                       *4 (SM)
MEMBRANES & LIPIDS
14  11/10  Lipids and Biological Membranes (TA taught)

15  11/15  Membrane Protein synthesis and stability
16  11/17  Membrane Proteins continued

CARBOHYDRATES
17  11/22  Basic chemistry                                                  *5 (HY)
    11/24  Thanksgiving Holiday

18  11/29  Glycozymes
19  12/01  Biological roles

    12/06  Last problem set due 5PM.

    12/09  Finals due by 5PM. (Bil's office or Stephen)


*n Problem set n handed out.

Last modified 27-SEP-2016